A COVID-19 patient at Norton Healthcare is the first in the world to participate in a randomized Phase 2 clinical study using low-dose selinexor. This oral drug, manufactured by Karyopharm Therapeutics Inc. and marketed as XPOVIO, is currently approved at higher doses by the U.S. Food and Drug Administration (FDA) as a treatment for cancer patients with relapsed or refractory multiple myeloma….
From Kelly C. McCants, M.D., medical director, Norton Heart & Vascular Institute Advanced Heart Failure and Recovery Program Physicians and surgeons throughout Kentucky and Southern Indiana are partnering through the Norton Heart & Vascular Institute Advanced Heart Failure and Recovery Program to focus on coordinated care, innovative technology, early intervention — and recovery — for…
Lori Lively’s gradual seven-year weight gain after an automobile accident raised her blood pressure, elevated her blood sugar level to diabetic range and worsened an existing heart condition. After the wreck and later, a hysterectomy, Lori’s formerly active lifestyle slowed, and her food choices started affecting her weight. On her petite, 5-foot frame, even a…
By Kelly C. McCants, M.D., medical director, Norton Heart & Vascular Institute Advanced Heart Failure and Recovery Program The stereotype of the heart failure patient often does not match the reality, which frequently leads to delayed diagnosis and treatment. If you look at epidemiological data, you’d think the heart failure patient is a white male,…
By Sydney Badon Seven years ago, my younger sister, Samantha, was diagnosed with epilepsy. Who would have thought that fluttering her eyes was actually a seizure? Sam didn’t seem herself, and so our pediatrician ordered a sleep-deprived electroencephalogram (EEG). This is a test that looks at how the brain works when it’s tired. At first,…
Radiologist Amanda Carricato, M.D., has joined Norton Healthcare, concentrating on diagnostic breast radiology. Her previous position was associate clinical professor in radiology at the University of Louisville. Dr. Carricato received her doctor of medicine degree from the University of Louisville School of Medicine. She completed a radiology residency and an internship in internal medicine, both…
Steven D. Glassman, M.D., orthopedic spine surgeon with at Norton Leatherman Spine, has authored the two most frequently cited articles on spinal deformity, according to a long-term analysis published in the journal Spine. The analysis listed the 100 top-cited articles on spinal deformities on record. Two articles by Dr. Glassman, each published in 2005, led…
Lynnwood Butler first noticed issues with his heart on Derby Day in 2013, when hypotension resulted in syncope. Two years later, the Louisville native had a heart attack at the end of his shift waiting on tables. He received an implantable cardioverter defibrillator (ICD). In 2016 and again in 2018, Lynnwood’s ICD was triggered. “It’s…
By Kelly C. McCants, M.D., medical director, Norton Heart & Vascular Institute Advanced Heart Failure and Recovery Program The day Keith Drury’s heart stopped, the last thing he remembers is driving to a job site near the Kentucky River. He doesn’t remember going into cardiac arrest, the CPR or the emergency helicopter flight to Norton…
Innovative technology allows providers with the Norton Heart & Vascular Institute Advanced Heart Failure and Recovery Program to see changes in patients’ conditions in real time, adjust their medications and diet as needed, and schedule clinical visits when necessary. We’re using technology to help patients’ hearts recover so they will not need advanced therapy, with…
In a study of adults, researchers found that those with epilepsy were twice as likely as adults without epilepsy to report feelings of depression in the previous year. Depressive thoughts or feelings can result from the many challenges that come with epilepsy, including stigma, fear of disclosure, unpredictable seizures, bullying, financial troubles and relationship changes….
Emaleigh Smith was born with a heart murmur, so her parents were on the lookout. At about 10 months, she started having unexplained eating issues, including food aversion. She started on feeding therapy. After about eight months, a computed tomography (CT) scan showed neuroblastoma in her chest, near vertebrae — hugging her aorta. Emaleigh was…