Research Archives - Norton Healthcare Provider

Phase 1 cystic fibrosis trial studying novel enzyme replacement therapy in adults

Patients 18 years of age and older with cystic fibrosis now have an option of participating in a Phase 1 trial of a novel, broad-spectrum, orally delivered enzyme replacement therapy for cystic fibrosis (CF). The [...]

Open-access, peer-reviewed medical journal accepting submissions

Norton Healthcare has launched a new, open-access medical journal to promote the sharing of innovation and ideas from the laboratory, the bedside and everyday practice. Norton Healthcare Medical Journal welcomes original articles related to medicine, […]

Louisville Business First has recognized Norton Healthcare and Norton Children’s research team members with its 2024 Health Care Heroes Innovator Award

Louisville Business First has recognized researchers at Norton Healthcare with its 2024 Health Care Heroes Innovator Award. The award honors those who break ground in the health care field by developing or implementing new technology, [...]

Butyrate-producing gut bacteria a promising avenue for Alzheimer’s treatment

Butyrate-producing gut bacteria are a promising target for preventing and treating memory loss associated with Alzheimer’s disease, according to research presented recently at the Alzheimer’s Association International Conference (AAIC) in Amsterdam, Netherlands. The research in […]

Natural killer cell leukemia trial underway

A human Phase 1 immunotherapy clinical trial is underway using natural killer cells, or NK cells, to target relapsed or refractory acute myeloid leukemia. Acute myeloid leukemia patients who have exhausted other treatment options are [...]

Glioblastoma immunotherapeutic SurVaxM studied at Norton Healthcare Brain Tumor Center

Researchers at the Norton Healthcare Brain Tumor Center are conducting a clinical trial to determine whether a promising new immunotherapy drug, SurVaxM, improves survivability of glioblastoma. SurVaxM targets survivin, a protein in 95% of glioblastomas [...]

Gilteritinib and venetoclax regimen yields encouraging results against FLT3-mutated AML

A new regimen of FMS-related tyrosine kinase 3 (FLT3) inhibitor gilteritinib and venetoclax was tolerable at standard doses and produced high response rates for advanced, FLT3-mutated acute myeloid leukemia (AML) in a multicenter Phase 1 [...]

Mental health and provider considerations when treating multiple sclerosis

As mental health disorders can be one of the “invisible” symptoms of multiple sclerosis (MS), mental health care can be a part of routine MS care through the regular use of screening tools and an [...]

Essentials of clinical trials

Clinical trials and studies, which are essential to the development of new drugs and treatments, need to be conducted under strict ethical, clinical and investigational structures. The most common are investigational trials with new medications [...]

Clinical research: Asking questions, sharing answers

Clinical research drives progress for every element of health and requires global collaboration. At Norton Healthcare alone, our research teams lead and contribute to studies about pediatric medicine, cancer, infectious diseases, cardiology, neurology, the spine, […]

Advancing the standard of cancer care and offering patients access to new therapies

Our goal is to offer every patient the option of the latest treatment available for their cancer. To do that, Norton Cancer Institute is participating in approximately 170 clinical trials at any time. These clinical [...]

First successful “valve-in-MAC” transcatheter mitral valve replacement in Louisville region

A multidisciplinary team of interventional cardiologists and a cardiothoracic surgeon performed Louisville’s first successful transcatheter replacement of a native mitral valve this week. The team with Norton Heart & Vascular Institute Structural Heart Program used […]

Category: Research