The patient A 12-year-old female presented to Norton Children’s Hospital emergency department with a one-week history of worsening right knee pain and swelling. There was no known trauma, but pain started after exertion in gym class. Initial MRI demonstrated an aggressive bone lesion involving almost the entire right femur. She underwent initial biopsy which confirmed…
Norton Cancer Institute Women’s Cancer Center has a beautiful new home in Medical Towers South (234 E. Gray St., on the downtown Louisville medical campus) that reflects our goal of treating the whole person. Clinicians share the remodeled downtown clinic space with the behavioral oncology team. Just outside the clinic door is a resource area…
At any time, Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine, is participating in dozens of clinical trials, representing a wide gamut of diagnoses and moving our understanding of childhood cancers forward. Norton Children’s Cancer Institute is a member of the Children’s Oncology Group and typically opens the same treatment studies and…
The patient A 31-year-old otherwise healthy man presented with an enlarging and increasingly symptomatic left posterior ilium tumor. Biopsy revealed high grade osteosarcoma. Additional staging studies demonstrated no distant metastases. He was treated with neoadjuvant MAP chemotherapy (methotrexate, Adriamycin, cisplatin). The challenge Pelvis osteosarcomas have lower overall survival than those of the extremities. Positive surgical…
Acute lymphoblastic leukemia (ALL) is the most common cancer among children, and its symptoms can be vague. Some, but not all, children with ALL present with a mix of symptoms that can include fever, fatigue and bleeding. Studies also have shown that about a third of children with ALL may have musculoskeletal symptoms. About three-quarters…
Every day at Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine, pharmacists round with the teams. We’re part of the decision-making process for hematology, oncology and stem cell transplant patients. Our goal is to help give these children the best possible outcome and keep them safe. For many patients, this involves following…
A new drug has revolutionized the care of children with moderate to severe hemophilia A, not only dramatically improving their quality of life but potentially eliminating future complications from the disease. Hemophilia A affects 1 in 5,000 male births, making it the most common congenital severe bleeding disorder. Until recently, the mainstay of treatment for…
Specialists at Norton Orthopedic Institute and Norton Cancer Institute work together in a team approach for treatment of bone and soft tissue tumors. As an orthopedic oncologist, I work closely with medical and radiation oncologists, musculoskeletal radiologists, and surgical pathologists to determine the best course of treatment for each patient. Timing of the various treatments…
Natalie F. Slone, D.O., a pediatric hematology/oncology specialist focusing on solid tumors and sarcomas in children and teens, has joined Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine. Her interest and passion for treating these cancers are in the challenge and the need to sometimes get creative to find the right solution. “It’s…
Patients with sickle cell disease (SCD) are at high risk for a broad range of acute and chronic conditions affecting many of the body’s systems and carrying a high association with morbidity. Given the broad range of potential manifestations of the disease, coordinating care among primary care providers, specialists, emergency departments, laboratories and hospitals can…
Addressing the emotional effects of cancer and its treatment on children and young adults can improve outcomes and help manage adverse effects of treatment. Norton Children’s is presenting a three-part series drawing from a recent continuing medical education opportunity with specialists from Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine. The presenters…
In its March 2021 revised guidelines for lung cancer screening, the U.S. Preventive Services Task Force (USPTF) noted Black men have a higher incidence of lung cancer than white men, and Black women have a lower incidence than white women. Reasons for the disparity were likely prevalence of smoking and other social risk factors, the…