First successful “valve-in-MAC” transcatheter mitral valve replacement in Louisville region

A multidisciplinary team of interventional cardiologists and a cardiothoracic surgeon performed Louisville’s first successful transcatheter replacement of a native mitral valve this week. The team with Norton Heart & Vascular Institute Structural Heart Program used […]

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Clinical trial summary: Venetoclax plus LDAC for adult AML patients at high risk of toxicity

Clinical challenge Acute myeloid leukemia (AML) patients ages 75 and older, and younger adults with comorbidities, are often ineligible to receive standard intensive chemotherapy due to high rates of toxicity and early mortality. As a [...]

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Study looks at how to detect RSV in adults

Norton Infectious Diseases Institute has been selected by Pfizer as the only site in United States to study how to effectively detect respiratory syncytial virus (RSV) in adults. “For the most part, RSV attention has [...]

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New guidelines for bone health assessment before elective spinal reconstruction

The Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for Perioperative Spine: Preoperative Osteoporosis Assessment recently was published in Neurosurgery. To develop these recommendations, the authors performed systematic review of the literature using national [...]

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Mental health and provider considerations when treating multiple sclerosis

As mental health disorders can be one of the “invisible” symptoms of multiple sclerosis (MS), mental health care can be a part of routine MS care through the regular use of screening tools and an [...]

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New evidence-based guidelines published for perioperative spine surgery assessments

New evidence-based guidelines covering five key perioperative spine assessments were issued recently by the Congress of Neurological Surgeons. The guidelines, published in the medical journal Neurosurgery, provide insight on the following: Preoperative osteoporosis assessment Preoperative […]

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Drug targeting prostate cancer cells to deliver radioisotope prolongs survival in trial

A cutting-edge new treatment specifically targets prostate cancer cells to deliver a tumor-killing radioisotope and helped extend patients’ lives longer in an international clinical trial (VISION Study), according to a study published in the New […]

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Access to evolving clinical science close to home

Norton Cancer Institute’s clinical research program was developed to ensure that cancer patients in our community and region have access to evolving clinical science. Guided by an experienced cadre of physicians and supported by a […]

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The latest advancements in pediatric cancer research for patients in Louisville and Southern Indiana

At any time, Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine, is participating in dozens of clinical trials, representing a wide gamut of diagnoses and moving our understanding of childhood cancers forward. […]

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Dual-pitch screws allow for inline revision of pedicle screws, study finds

Inline revision of pedicle screws without increasing the screw diameter can be achieved using dual-pitch screws with cancellous pitch in the vertebral body and cortical pitch in the pedicle, according to a study published in […]

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Study finds Enhanced Recovery After Surgery (ERAS) protocols help recovery after lumbar fusion

Enhanced Recovery After Surgery (ERAS) protocols have the potential to hasten recovery from lumbar fusion surgery for degenerative spine conditions, with reduced in-hospital opioid consumption and improved postoperative pain scores, according to a study published […]

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New use for tumor treatment fields device showing results for glioblastoma patients

After participating in a groundbreaking clinical trial that showed the Optune tumor treatment field device improves glioblastoma multiforme survival when combined with chemotherapy, neuro-oncologists at the Norton Healthcare Brain Tumor Center in Louisville, Kentucky, are […]

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