Research

Amber L. Pendleton, M.D., who led an effort to implement the principles of trauma-informed care across a Louisville, Kentucky, pediatric practice and community resources, is shown.

Implementing principles of trauma-informed care

Reviewed by Amber L. Pendleton, M.D. Implementing the principles of trauma-informed care across a primary care team and community resources provides an opportunity to focus on adverse childhood experiences and social-care needs, with the potential […]

As mental health disorders can be one of the “invisible” symptoms of multiple sclerosis (MS), mental health care can be a part of routine MS care through the regular use of screening tools and an integrated approach to treatment.

Mental health and provider considerations when treating multiple sclerosis

As mental health disorders can be one of the “invisible” symptoms of multiple sclerosis (MS), mental health care can be a part of routine MS care through the regular use of screening tools and an [...]

David A. Sun, M.D., Ph.D., reviews a patient’s response to a brain tumor clinical trial

Essentials of clinical trials

Clinical trials and studies, which are essential to the development of new drugs and treatments, need to be conducted under strict ethical, clinical and investigational structures. The most common are investigational trials with new medications [...]

Study of Paxlovid for children with COVID-19 underway at Norton Children’s Research Institute

Norton Children’s Research Institute, affiliated with the UofL School of Medicine, is involved in a study to evaluate the safety, pharmacokinetics and efficacy of nirmatrelvir/ritonavir (authorized as Paxlovid in older children and adults) in symptomatic [...]

Clinical research: Asking questions, sharing answers

Clinical research drives progress for every element of health and requires global collaboration. At Norton Healthcare alone, our research teams lead and contribute to studies about pediatric medicine, cancer, infectious diseases, cardiology, neurology, the spine, […]

Advancing the standard of cancer care and offering patients access to new therapies

Our goal is to offer every patient the option of the latest treatment available for their cancer. To do that, Norton Cancer Institute is participating in approximately 170 clinical trials at any time. These clinical [...]

Study shows low-dose cadmium threshold for testicular ferroptosis in mice

Cadmium, a natural element used for rechargeable batteries and other industrial applications, can induce a novel type of testicular cell death in mice after low-dose exposure, according to a groundbreaking study. Cadmium is known to […]

First successful “valve-in-MAC” transcatheter mitral valve replacement in Louisville region

A multidisciplinary team of interventional cardiologists and a cardiothoracic surgeon performed Louisville’s first successful transcatheter replacement of a native mitral valve this week. The team with Norton Heart & Vascular Institute Structural Heart Program used […]

Clinical trial summary: Venetoclax plus LDAC for adult AML patients at high risk of toxicity

Clinical challenge Acute myeloid leukemia (AML) patients ages 75 and older, and younger adults with comorbidities, are often ineligible to receive standard intensive chemotherapy due to high rates of toxicity and early mortality. As a [...]

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Provider Spotlight

Alaina C. Sewell, APRN

Alaina C. Sewell, APRN, will work at the Springhurst location of Norton Community Medical Associates – Endocrinology.

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PSMA PET scan is catching cancer earlier and with greater accuracy than ever before

Accurate imaging is a crucial component of prostate cancer management for a number of reasons, including tumor localization, disease staging and detecting recurrence. Prostate-specific membrane antigen positron emission tomography (PSMA PET) scans offer an imaging […]

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What to expect when referring to a pediatric epileptologist

Pediatric epileptologists are specialized pediatric neurologists who help to confirm the diagnosis of epilepsy, discover what is causing a child’s seizures and work to find an individualized management strategy considering concomitant medical issues. Referral to […]

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Treatments for refractory overactive bladder and urge incontinence

In addition to Botox, patients with overactive bladder and urge incontinence who have failed to improve on medication can choose from two procedures that work by modulating nerve activity: sacral neuromodulation and percutaneous nerve stimulation. [...]

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Implementing principles of trauma-informed care

Reviewed by Amber L. Pendleton, M.D. Implementing the principles of trauma-informed care across a primary care team and community resources provides an opportunity to focus on adverse childhood experiences and social-care needs, with the potential […]

Read Full Story

Mental health and provider considerations when treating multiple sclerosis

As mental health disorders can be one of the “invisible” symptoms of multiple sclerosis (MS), mental health care can be a part of routine MS care through the regular use of screening tools and an [...]

Read Full Story

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