Kaylyn D. Sinicrope, M.D., local principal investigator on a SurVaxM glioblastoma trial, is shown.

Glioblastoma immunotherapeutic SurVaxM studied at Norton Healthcare Brain Tumor Center

Researchers at the Norton Healthcare Brain Tumor Center are conducting a clinical trial to determine whether a promising new immunotherapy drug, SurVaxM, improves survivability of glioblastoma. SurVaxM targets survivin, a protein in 95% of glioblastomas [...]

Joseph J. Maly, M.D., with Norton Cancer Institute, is shown. Dr. Maly co-authored a recent study on a gilteritinib and venetoclax regimen for FLT3-mutated AML.

Gilteritinib and venetoclax regimen yields encouraging results against FLT3-mutated AML

A new regimen of FMS-related tyrosine kinase 3 (FLT3) inhibitor gilteritinib and venetoclax was tolerable at standard doses and produced high response rates for advanced, FLT3-mutated acute myeloid leukemia (AML) in a multicenter Phase 1 [...]

Amber L. Pendleton, M.D., who led an effort to implement the principles of trauma-informed care across a Louisville, Kentucky, pediatric practice and community resources, is shown.

Implementing principles of trauma-informed care

Reviewed by Amber L. Pendleton, M.D. Implementing the principles of trauma-informed care across a primary care team and community resources provides an opportunity to focus on adverse childhood experiences and social-care needs, with the potential […]

As mental health disorders can be one of the “invisible” symptoms of multiple sclerosis (MS), mental health care can be a part of routine MS care through the regular use of screening tools and an integrated approach to treatment.

Mental health and provider considerations when treating multiple sclerosis

As mental health disorders can be one of the “invisible” symptoms of multiple sclerosis (MS), mental health care can be a part of routine MS care through the regular use of screening tools and an [...]

David A. Sun, M.D., Ph.D., reviews a patient’s response to a brain tumor clinical trial

Essentials of clinical trials

Clinical trials and studies, which are essential to the development of new drugs and treatments, need to be conducted under strict ethical, clinical and investigational structures. The most common are investigational trials with new medications [...]

Study of Paxlovid for children with COVID-19 underway at Norton Children’s Research Institute

Norton Children’s Research Institute, affiliated with the UofL School of Medicine, is involved in a study to evaluate the safety, pharmacokinetics and efficacy of nirmatrelvir/ritonavir (authorized as Paxlovid in older children and adults) in symptomatic [...]

Clinical research: Asking questions, sharing answers

Clinical research drives progress for every element of health and requires global collaboration. At Norton Healthcare alone, our research teams lead and contribute to studies about pediatric medicine, cancer, infectious diseases, cardiology, neurology, the spine, […]

Advancing the standard of cancer care and offering patients access to new therapies

Our goal is to offer every patient the option of the latest treatment available for their cancer. To do that, Norton Cancer Institute is participating in approximately 170 clinical trials at any time. These clinical [...]

Study shows low-dose cadmium threshold for testicular ferroptosis in mice

Cadmium, a natural element used for rechargeable batteries and other industrial applications, can induce a novel type of testicular cell death in mice after low-dose exposure, according to a groundbreaking study. Cadmium is known to […]

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Provider Spotlight

Keith A. McLean, M.D.

Norton Heart & Vascular Institute welcomes Keith A. McLean, M.D., cardiologist; office hours dedicated to residents of Madison and surrounding communities.

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Stephanie A. Merimee, M.D., orthopedic surgeon and Louisville native, joining Norton Louisville Arm & Hand

Stephanie A. Merimee, M.D., an orthopedic surgeon, has joined the team at Norton Louisville Arm & Hand. Dr. Merimee has a medical degree from the University of Louisville School of Medicine. She completed her residency […]

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August 2023 Norton Children’s Medical Group New Providers

Rebecca M. Callahan, D.O. ­ Pediatric Hospital Medicine Logan M. Eberly, M.D. Pediatric Cardiology Dominique C. Elmore, D.O. ­ Pediatric Emergency Medicine Allison N. Lyle, M.D. ­ Neonatology Aaron J. Samide, M.D. Pediatric Hospital Medicine […]

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August 2023 Norton Medical Group new providers

Shawn W. Adams, M.D. Neurosurgery Megan M. Bertke, M.D. Emergency Medicine Samrath Bhimani, M.D. Hip Orthopedic Surgery Abhishek Bose, M.D. Electrophysiology Joshua H. Brandon, M.D. Family Medicine Rabia G. Buridi, M.D. Stroke Neurology Robert S. […]

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Benefits of ultrasound-guided fine needle aspiration biopsy

Fine needle aspiration (FNA) can provide a timelier evaluation of neck masses than open biopsy, thus saving time, money and potentially improving health outcomes with earlier diagnosis and treatment. Fine needle aspiration for head and […]

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Lutetium Lu 177 dotatate available for advanced neuroendocrine tumor treatment

Norton Cancer Institute is the only site in Louisville offering lutetium Lu 177 dotatate (Lutathera), a second-line treatment targeting advanced-stage neuroendocrine tumors in adult patients. The drug is indicated when a patient starts to lose [...]

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