Clinical trial for HER2-positive metastatic colorectal cancer shows promising result

The patient A 55-year-old woman developed increasing difficulties with constipation and abdominal discomfort over the course of several weeks. She then developed nausea with vomiting. She was found to have an obstructing colon cancer with [...]

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Lumps in the neck are typically harmless, but sometimes can be cause for further investigation. Here’s what providers should know.

A painless lump on the side of the neck can have many causes, including benign conditions, infections or more serious diseases. Most commonly, swollen lymph nodes are the result of  infection. Less commonly, it can […]

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Norton Cancer Institute enrolling patients for gotistobart (ONC-392) Phase 3 trial

Norton Cancer Institute is enrolling metastatic lung cancer patients in a Phase 3 clinical trial to test a promising new anti-CLTA-4 antibody, gotistobart (ONC-392). The study will test whether gotistobart is more effective than the [...]

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Diagnosing early stage lung cancer with robotic bronchoscopy lung nodule biopsy

The patient A 67-year-old woman with a past medical history of chronic obstructive pulmonary disease and emphysema presented with a spiculated right upper-lobe nodule that was previously 8 millimeters in size on CT scan of […]

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Lung cancer screening guidelines

The U.S. Preventive Services Task Force updated its lung cancer screening guidelines in 2021 to include younger patients and those who smoked less than the previous recommendation. The current USPSTF lung cancer screening guidelines are [...]

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Late-stage lung cancer diagnoses weigh heavily on the socially disadvantaged

As a medical oncologist at Norton Cancer Institute, I’ve seen remarkable advances in how we treat lung cancer. Lung cancers caught early can now often be successfully treated. Unfortunately, Kentucky has a massive lung cancer [...]

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Natural killer cell leukemia trial underway

A human Phase 1 immunotherapy clinical trial is underway using natural killer cells, or NK cells, to target relapsed or refractory acute myeloid leukemia. Acute myeloid leukemia patients who have exhausted other treatment options are [...]

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When to consider genetic testing for breast cancer

At some point in their life, 1 in 8 women will develop breast cancer. Approximately 20% of breast cancer cases are familial, affecting two or more women in the same family, usually at a later […]

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Benefits of ultrasound-guided fine needle aspiration biopsy

Fine needle aspiration (FNA) can provide a timelier evaluation of neck masses than open biopsy, thus saving time, money and potentially improving health outcomes with earlier diagnosis and treatment. Fine needle aspiration for head and […]

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Lutetium Lu 177 dotatate available for advanced neuroendocrine tumor treatment

Norton Cancer Institute is the only site in Louisville offering lutetium Lu 177 dotatate (Lutathera), a second-line treatment targeting advanced-stage neuroendocrine tumors in adult patients. The drug is indicated when a patient starts to lose [...]

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Gastric cancer red flags

The prognosis for gastric cancer is closely tied to the stage of the diagnosis. When found early, gastric cancer has a better survival rate. “Given the difference early diagnosis can make, it’s important that clinicians [...]

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Paul A. Tennant, M.D., joins Norton Cancer Institute

Paul A. Tennant, M.D., has joined Norton Cancer Institute as a head and neck surgical oncologist. He treats complex benign and malignant conditions of the head and neck. Dr. Tennant sees patients at Norton Cancer […]

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