Butyrate-producing gut bacteria are a promising target for preventing and treating memory loss associated with Alzheimer’s disease, according to research presented recently at the Alzheimer’s Association International Conference (AAIC) in Amsterdam, Netherlands. The research in 3XTg mouse model demonstrated that oral administration of tributyrin mitigates age-associated loss of butyrate-producing bacteria and prevents the decline in…
A human Phase 1 immunotherapy clinical trial is underway using natural killer cells, or NK cells, to target relapsed or refractory acute myeloid leukemia. Acute myeloid leukemia patients who have exhausted other treatment options are potential candidates for the trial, ClinicalTrials.gov ID NCT05470140. The trial uses cytokine-reprogrammed, non-engineered, “off-the-shelf” NK cells from a healthy donor….
Jonathan P. Boland, M.D. Emergency Medicine James C. Gray IV, M.D. Emergency Medicine Stephanie Miles, M.D. Family Medicine Vladimir Pulgaron, M.D. Family Medicine Steven J. Radtke, M.D. Urogynecology Cindy Truong, D.O. Internal Medicine Michael McCool II, PA-C Neurosurgery Alexandria J. Bassler, APRN Thoracic Surgery Tracy C. Jensen, APRN Internal Medicine Whitney L. King, APRN Cardiology…
At some point in their life, 1 in 8 women will develop breast cancer. Approximately 20% of breast cancer cases are familial, affecting two or more women in the same family, usually at a later age. An estimated 5% to 10% of breast cancers are caused by a genetic mutation, called hereditary breast cancer. Red…
Primary care and sports medicine providers hear frequently from patients about hip and knee pain, especially among older adults. The threshold for referral to an orthopedic specialist for possible joint replacement focuses on pain and disability. Most hip and knee replacements are done between ages 50 and 80, but hip and knee replacements have been…
Stephanie A. Merimee, M.D., an orthopedic surgeon, has joined the team at Norton Louisville Arm & Hand. Dr. Merimee has a medical degree from the University of Louisville School of Medicine. She completed her residency at the University of South Florida and Florida Orthopaedic Institute in Tampa, Florida. Prior to coming back to Louisville, Dr….
Shawn W. Adams, M.D. Neurosurgery Megan M. Bertke, M.D. Emergency Medicine Samrath Bhimani, M.D. Hip Orthopedic Surgery Abhishek Bose, M.D. Electrophysiology Joshua H. Brandon, M.D. Family Medicine Rabia G. Buridi, M.D. Stroke Neurology Robert S. Butler, M.D. Emergency Medicine Stephen Cawood, M.D. Emergency Medicine Benjamin T. Cunningham, M.D. Emergency Medicine Daniel Frick, D.O. Emergency Medicine…
Fine needle aspiration (FNA) can provide a timelier evaluation of neck masses than open biopsy, thus saving time, money and potentially improving health outcomes with earlier diagnosis and treatment. Fine needle aspiration for head and neck masses Masses felt by the clinician or detected with imaging scans often require further testing. Options for obtaining tissue…
Norton Cancer Institute is the only site in Louisville offering lutetium Lu 177 dotatate (Lutathera), a second-line treatment targeting advanced-stage neuroendocrine tumors in adult patients. The drug is indicated when a patient starts to lose response to the first-line therapies, lanreotide (Somatuline) and octreotide acetate (Sandostatin). Norton Cancer Institute To refer a patient to Norton…
The shoulder joint is a complex combination of ligaments, muscles, bones and tendons. All these structures must function correctly to keep the joint in alignment, or the patient could experience pain, decreased range of motion, weakness and discomfort. Athletes in throwing sports must take special care to keep their shoulder healthy or risk developing conditions…
Norton Heart & Vascular Institute welcomes Keith A. McLean, M.D., cardiologist, to Norton King’s Daughters’ Health in Madison, Indiana. The office is located in the Norton King’s Daughters’ Health Downtown Medical Building at 630 N. Broadway. With the addition of Dr. McLean, the office will have three providers seeing patients Monday through Friday. Dr. McLean…
Patients who need a hip replacement often ask about anterior versus posterior hip replacement approaches. Both approaches work well over the long term, but the anterior approach has the advantage of a speedier recovery, according to Kevin J. Himschoot, M.D., an orthopedic surgeon and reconstructive surgery specialist with Norton Orthopedic Institute. Patients who have had a…