Sotatercept was recently approved by the Food and Drug Administration (FDA) to treat adults with pulmonary arterial hypertension (PAH) after completing a Phase 3 clinical trial at Norton Pulmonary Specialists and other leading pulmonary hypertension centers. Sotatercept, sold under the brand name Winrevair, is a new class of therapy for pulmonary arterial hypertension. It has…
Artificial intelligence (AI) like ChatGPT can compose essays or emails, write computer code, even generate art, but how well can it manage complex patient care? A team that included Norton Healthcare researchers decided to find out. They compared ChatGPT’s recommendations for managing an 81-year-old patient with nonresolving pneumonia with those of a pulmonary specialist. “What…
John T. Garner, M.D. Hospital Medicine Ishan J. Parikh, D.O. Hospital Medicine Aleksandr Pevtsov, D.O. Emergency Medicine Elizabeth Fahey, PA-C Orthopedic Hand Surgery Amy Seldon, PA-C Emergency Medicine Gregory A. Hart, APRN Emergency Medicine Amy B. Hughes, APRN Emergency Medicine Kathryn A. Karem, APRN Urgent Care Jason W. Raggard, APRN Emergency Medicine Ashley R. Trautwein,…
Prehabilitation, or “prehab,” refers to optimizing general health and well-being before surgery to improve surgical outcomes. Prehab takes a multidisciplinary approach, focusing on strength and aerobic exercises, nutrition, smoking cessation, alcohol reduction, and psychological factors such as mitigating stress, anxiety and depression. The approach is primarily designed for patients who are at the highest risk…
Patients 18 years of age and older with cystic fibrosis now have an option of participating in a Phase 1 trial of a novel, broad-spectrum, orally delivered enzyme replacement therapy for cystic fibrosis (CF). The randomized, active-treatment trial is testing the safety, tolerability and effect of four dose levels of ANG003, a compound developed by…
The patient A 64-year-old woman tripped after “missing a step,” fracturing her left tibial plateau and resulting in deformity of the joint. This was managed conservatively, with a leg brace removing weight from the extremity. She developed persistent numbness and tingling in her left leg, as well as weakness. She was evaluated in the Norton…
Paul A. Kniery, M.D. Internal Medicine Stephen Love, M.D. Behavioral Medicine Sarah A. Mayfield, M.D. Internal Medicine Emmanuel A. Nidhiry, M.D. Medical Oncology and Hematology Anupama Raghuram, M.D. Infectious Diseases Elizabeth Fahey, PA-C Hand Surgery Kathryn Hardesty, PA-C General Surgery Kyla M. Byard, APRN Family Medicine Stacie S. Cheney, APRN Family Medicine Anna N. Ertel,…
In 2023, the Food and Drug Administration (FDA) approved lecanemab (brand name Leqembi) for the treatment of Alzheimer’s disease. Lecanemab is the first widely used medication in a new class of anti-amyloid agents for the treatment of patients with mild cognitive impairment (MCI) or early stages of Alzheimer’s disease. This is the first new Alzheimer’s…
Norton Arm & Hand Institute is the new name for Norton Louisville Arm & Hand, as of March 1, 2024. The goal of Norton Arm & Hand Institute is to be a destination program by establishing itself as a thought and practice leader in upper extremity care. The institute is founded upon five pillars: clinical…
The Norton Healthcare Antimicrobial Stewardship Program was recognized this year as the first and only antimicrobial stewardship center of excellence in the United States by the British Society of Antimicrobial Chemotherapy. The international collaboration is part of the society’s new Global Antimicrobial Stewardship Accreditation Scheme. The accreditation process, developed by BSAC and led by experts…
Norton Cancer Institute is enrolling metastatic lung cancer patients in a Phase 3 clinical trial to test a promising new anti-CLTA-4 antibody, gotistobart (ONC-392). The study will test whether gotistobart is more effective than the chemotherapy agent docetaxel in prolonging life in patients with metastatic, non-small cell lung cancer whose disease progressed on anti-PD-1/PD-L1 antibody…
Christopher P. Rhyne, M.D., is a headache medicine specialist at Norton Neuroscience Institute. He earned his medical degree from Windsor University School of Medicine, St. Kitts, West Indies. He completed his residency in family medicine at the University of Illinois Chicago. Dr. Rhyne comes to Norton Neuroscience Institute Headache Center from the Diamond Headache Clinic…