Migraine affects 37 million men, women and children in the United States and ranks among the top 10 most disabling medical conditions, according to the World Health Organization. More than 90% of patients report that migraine interferes with education, career and social activities – making early recognition and treatment in pediatric populations particularly crucial. Paul…
The patient An 18-year-old male with a history of heart transplantation for cardiomyopathy after a durable ventricular assist device presented with progressive cardiac allograft vasculopathy (CAV) and severe diastolic graft failure. The patient presented to the cardiac intensive care unit after a recovered cardiac arrest in extremis with impending multiorgan failure. He initially underwent placement…
Provider Team The patient The patient is a now 13-year-old girl with a history of anxiety and headaches dating back to approximately age 7, although she did not present to neurology until age 9. At that time, she was reporting approximately 15 out of 30 headache days per month and was meeting criteria for chronic…
Pediatric migraine management requires a nuanced approach that differs significantly from adult protocols. While migraine affects up to 10% of children and adolescents, treatment decisions must account for developmental considerations, family dynamics and the substantial placebo effect observed in younger patients. This evidence-based guide synthesizes current best practices for clinicians managing pediatric migraine, from initial…
Myocarditis represents a significant cause of morbidity and mortality in pediatric patients, yet its clinical presentation can be deceptively subtle. As inflammation of the heart muscle and conduction system, myocarditis affects the heart’s ability to contract effectively and maintain normal rhythm, potentially leading to sudden cardiac death even in previously healthy children. Epidemiology and risk…
The multidisciplinary Norton Children’s Cancer Predisposition Program is designed to identify, monitor and support children who have inherited genetic conditions that increase their lifetime risk of cancer. The program established in November 2024 is a collaborative effort between Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine, and Norton Children’s Genetics Center, also…
Cancer care offered through Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine, is ranked among the top 50 pediatric cancer programs nationwide by U.S. News & World Report in its 2024–2025 Best Children’s Hospitals rankings. This recognition reflects the commitment to excellence at Norton Children’s Cancer Institute, evident in a comprehensive array…
Norton Children’s, a comprehensive pediatric health care system based in Louisville, plans to build a new pediatric care campus that will include a full-service hospital for children with complex medical needs, research facilities and expanded specialty services. The project marks a major expansion for the health care system and will feature the system’s second dedicated…
Mustafa Barbour, M.D., pediatric neuro-oncologist with Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine, is working to advance pediatric neuro-oncology care in Kentucky, where the incidence of pediatric brain tumors exceeds the national average. In response, Dr. Barbour, who leads the Norton Children’s Brain & Spinal Tumor program, helps lead new research…
Shelby M Doughty, APRN Pediatric Critical Care Medicine
[vc_row][vc_column][vc_column_text]Norton Children’s Pulmonology, affiliated with the UofL School of Medicine, is actively recruiting adolescent participants who meet criteria for a clinical trial of two inhaled treatments for asthma. According to the Centers for Disease Control and Prevention, more than 6 million children in the United States have asthma. Even with sufficient symptom management, asthma exacerbations…