Norton Children’s nationally ranked for pediatric cancer care by U.S. News & World Report

Cancer care offered through Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine, is ranked among the top 50 pediatric cancer programs nationwide by U.S. News & World Report in its 2024–2025 Best […]

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Leading with compassion, Mustafa Barbour, M.D., advances pediatric neuro-oncology care in Kentucky

Mustafa Barbour, M.D., pediatric neuro-oncologist with Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine, is working to advance pediatric neuro-oncology care in Kentucky, where the incidence of pediatric brain tumors exceeds the […]

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Managing cognitive deficits in childhood cancer survivors

After improving pediatric cancer survival from nearly nil in the 1950s to more than 85% today, health care providers face new challenges, especially long-term cognitive deficits associated with chemotherapy. In addition to attacking cancer cells, […]

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Study shows ETV failure in midline gliomas may indicate H3K27M mutation

Failure of endoscopic third ventriculostomy (ETV) to relieve hydrocephalus in patients with midline brain tumors may be an early indication of an underlying histone H3K27M mutation, according to a recently published study.

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Identifying and managing late effects of pediatric cancer therapy

Pediatric oncology’s remarkable strides improving survival for children with cancer also has brought a new set of long-term health implications.

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Norton Children’s names new pediatric cancer chief

Norton Children’s has named a new physician to lead its cancer institute.

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DFMO medulloblastoma clinical trial examines drug’s effectiveness for high-risk cases

Researchers are recruiting pediatric medulloblastoma patients for a novel use of difluoromethylornithine (DFMO) to prevent relapse. The multisite study, sponsored by the Beat Childhood Cancer Consortium and led by Michael Angelo C. Huang, M.D., pediatric [...]

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When to refer a pediatric anemia patient

Infants and children can be prone to anemia for a variety of reasons throughout their first years of life and adolescence. Anemia can be caused by diet, blood loss or other health conditions. Signs and […]

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Case study: Shunt relieves pressure from arachnoid brain cyst, allowing boy to continue leukemia treatment

The patient A 4-year-old boy presented to the hospital with fever, fatigue and weakness. He also complained of blurry vision. He had recently had nose bleeds and oral bleeding. A complete blood count showed pancytopenia, [...]

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Pediatricians’ primer on childhood CNS tumors

Tumors in the central nervous system (CNS) account for 20% of childhood cancers, with 5.65 cases and 0.72 deaths per 100,000 children under 14 in the United States. Brain tumors are second only to acute […]

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MEK Inhibitor shrinks large hypothalamic enhancing tumor in teen

The patient A 14-year-old female presented with worsening headache and deterioration of vision especially in the left eye. MRI detected a large hypothalamic enhancing tumor causing mass effect on the optic nerves. The pituitary gland […]

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Classification and treatment of pediatric cancerous brain tumor, medulloblastoma

Medulloblastoma is one of the most common malignant brain tumors in children, with cases tending to surface around ages 4 or 5. Currently, the treatment protocol is resection of as much of the tumor as […]

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