Adult Services, Medical Group

November 2023 Norton Medical Group new providers

George Gad, M.D. Hospital Medicine Nathan Gonda, D.O. Emergency Medicine Sarah B. Radtke, M.D. Obstetrics/ Gynecology Lauren M. Strait, M.D. Vascular Surgery Molly E. Tuller, M.D. Obstetrics/Gynecology Tracey D. Wolford, M.D. Gastroenterology Maureen Carberry, PA-C Colon and Rectal Surgery Caitlin C. Crowley, PA-C Pulmonology Emily Mathews, PA-C Emergency Medicine Felecia Q. Carey, APRN Urgent Care…

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Adult Services, Diabetes, Pediatric Services, Research

Tzield may delay Stage 3 Type 1 diabetes in adults and children

Recently approved Tzield (teplizumab-mzwv), is delivering breakthrough results that suggest it may delay the onset of Stage 3 Type 1 diabetes by an average of two years. The first-in-class drug is approved for adults and children ages 8 and older with Stage 2 Type 1 diabetes. “Delaying the onset of Stage 3 not only postpones…

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Diabetes, Pediatric Services, Research

Ultra-fast-acting inhaled insulin, Afrezza, trialed at Norton Children’s Endocrinology

Afrezza inhaled insulin, currently approved for adults, is being tested for children in a clinical trial at Wendy Novak Diabetes Institute, a part of Norton Children’s Endocrinology, affiliated with the UofL School of Medicine. Norton Children’s is one of 40 sites nationally participating in the Phase 3 trial. Afrezza is an ultra-fast-acting inhaled mealtime insulin,…

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Oncology/Hematology, Pediatric Services, Research

DFMO medulloblastoma clinical trial examines drug’s effectiveness for high-risk cases

Researchers are recruiting pediatric medulloblastoma patients for a novel use of difluoromethylornithine (DFMO) to prevent relapse. The multisite study, sponsored by the Beat Childhood Cancer Consortium and led by Michael Angelo C. Huang, M.D., pediatric neuro-oncologist at Norton Children’s Cancer Institute, affiliated with the UofL School of Medicine, looks at whether DFMO offers a new…

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Adult Services, Neuroscience, Research

Butyrate-producing gut bacteria a promising avenue for Alzheimer’s treatment

Butyrate-producing gut bacteria are a promising target for preventing and treating memory loss associated with Alzheimer’s disease, according to research presented recently at the Alzheimer’s Association International Conference (AAIC) in Amsterdam, Netherlands. The research in 3XTg mouse model demonstrated that oral administration of tributyrin mitigates age-associated loss of butyrate-producing bacteria and prevents the decline in…

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Cardiovascular, Pediatric Services, Research

Norwood vs. COMPSII for critical left heart obstruction with prior palliation

Surgeons face two choices for infants with critical left heart obstruction who have had prior hybrid palliation: a Norwood operation or a comprehensive stage II (COMPSII). The critical left heart obstruction cohort of the multi-institutional Congenital Heart Surgeons’ Society looked at patient characteristics and outcomes for these two pathways. The study, “Norwood Operation Versus Comprehensive…

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Adult Services, Oncology/Hematology, Research

Natural killer cell leukemia trial underway

A human Phase 1 immunotherapy clinical trial is underway using natural killer cells, or NK cells, to target relapsed or refractory acute myeloid leukemia. Acute myeloid leukemia patients who have exhausted other treatment options are potential candidates for the trial, ClinicalTrials.gov ID NCT05470140. The trial uses cytokine-reprogrammed, non-engineered, “off-the-shelf” NK cells from a healthy donor….

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Adult Services, Medical Group

October 2023 Norton Medical Group new providers

Jonathan P. Boland, M.D. Emergency Medicine James C. Gray IV, M.D. Emergency Medicine Stephanie Miles, M.D. Family Medicine Vladimir Pulgaron, M.D. Family Medicine Steven J. Radtke, M.D. Urogynecology Cindy Truong, D.O. Internal Medicine Michael McCool II, PA-C Neurosurgery Alexandria J. Bassler, APRN Thoracic Surgery Tracy C. Jensen, APRN Internal Medicine Whitney L. King, APRN Cardiology…

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Adult Services, CME, Oncology/Hematology

Garlove Lectureship features advancements in medicine, a look at new discoveries and technologies

The 28th Gail Klein Garlove Lectureship on Nov. 1 is titled “Advancing Precision Medicine Through New Discoveries and Technologies,” and will be presented by Sameek Roychowdhury, M.D., Ph.D., medical director of the cancer genomics laboratory and medical oncologist at The Ohio State University Comprehensive Cancer Center – James. The event is hosted by Norton Healthcare…

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Adult Services, Oncology/Hematology

When to consider genetic testing for breast cancer

At some point in their life, 1 in 8 women will develop breast cancer. Approximately 20% of breast cancer cases are familial, affecting two or more women in the same family, usually at a later age. An estimated 5% to 10% of breast cancers are caused by a genetic mutation, called hereditary breast cancer. Red…

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Endocrinology, Pediatric Services

Thyroid weight gain myths and surprises

Patients often suspect a thyroid condition is responsible for their weight gain or their weight loss struggles. Much of the stimulus for this belief is based on the internet, according to Lisal J. Folsom, M.D., M.S., a pediatric and adult endocrinologist with Norton Community Medical Associates and Norton Children’s Endocrinology, affiliated with the UofL School…

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Adult Services, Orthopedics

Orthopedic referral guidelines: Hip and knee joint replacement

Primary care and sports medicine providers hear frequently from patients about hip and knee pain, especially among older adults. The threshold for referral to an orthopedic specialist for possible joint replacement focuses on pain and disability. Most hip and knee replacements are done between ages 50 and 80, but hip and knee replacements have been…

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