Bevacizumab shown to reduce radiation necrosis in clinical trial

Clinical challenge Radiation necrosis of the brain causes debilitating headaches, recurrent seizures, focal neurological deficits and subcortical neurocognitive slowing. Radiation necrosis occurs in about a fifth of patients who receive stereotactic radiation therapy (SRT) or [...]

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Surgical intervention is an effective treatment for stroke

A stroke occurs when blood flow to the brain is disrupted, either when a blood vessel is blocked (an ischemic stroke) or when a blood vessel bursts (hemorrhagic stroke). The brain uses constant blood flow […]

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Spinal tumor case study: Mass blocked 90% of canal

The patient A 27-year-old female presented with five months of progressive quadriparesis and paresthesias affecting both upper and lower extremities. She initially presented to her primary care provider five months prior, while eight months pregnant, […]

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New surgeons allow multidisciplinary head and neck tumor care from diagnosis through follow-up

With the addition of a pair of surgeons, Norton Cancer Institute Head and Neck Tumor Program is now a fully integrated multidisciplinary team caring for patients from diagnosis through treatment to follow-up. Paul A. Tennant, […]

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Mechanical thrombectomy for middle cerebral artery stroke leads to discharge 2 days later with NIH Stroke Scale score of 0

Incident details:   Date: 4/26/2022 Patient: Male Age: 66 Arrival to emergency department:11 a.m. Tom L. Yao, M.D., endovascular neurosurgeon, Norton Neuroscience Institute   Nadeem A. Talpur, M.D. stroke neurologist, Norton Neuroscience Institute   Richard […]

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Dementia care for communities of color

Dementia is an umbrella term that includes a range of symptoms associated with cognitive decline. Perhaps one of the best known and most common types — Alzheimer’s dementia — represents 60% to 80% of all […]

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The window of stroke care

Time saved is brain saved when it comes to stroke care. “Stroke is one of the leading causes of death in the U.S,” said Shervin R. Dashti, M.D., Ph.D., endovascular neurosurgeon and spine surgeon at […]

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Imaging could lead to further expansion of tPA window

Additional data could lead to stronger guidelines extending the tPA window for ischemic strokes beyond the current 4½ hour limit in coming years, according to a Norton Neuroscience Institute stroke specialist. A common scenario faced [...]

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Phase 3 trial examines whether donanemab can prevent Alzheimer’s

Patients who are cognitively normal but have a family history or other concern about developing Alzheimer’s may be eligible to participate in a study looking at whether an investigational drug can slow or prevent the [...]

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When are headache symptoms a red flag for a more serious condition?

When are headache symptoms consistent with migraine or red flags of a condition warranting urgent or emergency medical attention? Migraine occurs in a recurring pattern and can be diagnosed clinically, without MRI or other tests, [...]

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Is it a stroke or does it just present like one?

Ischemic stroke is the among the leading causes of death in the United States, but so-called stroke mimics and stroke chameleons also can be deadly. At a recent presentation, Bryan J. Eckerle, M.D., neurologist with […]

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Delirium and dementia: Overlapping symptoms, but distinct syndromes

Delirium and dementia are distinct clinical syndromes, with symptoms that frequently overlap. Delirium is a neuropsychiatric condition that occurs acutely, a sudden and definite decline from the baseline, progressing over hours, days, or weeks, but [...]

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