Adult Services, Diabetes, Endocrinology, Pediatric Services, Research

Advancing diabetes research: Norton Healthcare becomes one of 10 organizations to join national islet cell network

Norton Healthcare and Norton Children’s are now contributing vital resources to diabetes research efforts nationwide. As a new member of the Integrated Islet Distribution Program (IIDP), the Norton Islet Cell Research and Transplant Program, housed within Wendy Novak Diabetes Institute, supplied its first round of human pancreatic islet cells to researchers across the country, including…

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Pediatric Services, Pulmonology, Research

Clinical trial now enrolling to evaluate efficacy of inhalers for pediatric asthma patients

[vc_row][vc_column][vc_column_text]Norton Children’s Pulmonology, affiliated with the UofL School of Medicine, is actively recruiting adolescent participants who meet criteria for a clinical trial of two inhaled treatments for asthma. According to the Centers for Disease Control and Prevention, more than 6 million children in the United States have asthma. Even with sufficient symptom management, asthma exacerbations…

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Adult Services, Neuro-Oncology, Pediatric Services, Research

Study shows ETV failure in midline gliomas may indicate H3K27M mutation

Failure of endoscopic third ventriculostomy (ETV) to relieve hydrocephalus in patients with midline brain tumors may be an early indication of an underlying histone H3K27M mutation, according to a recently published study.

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Adult Services, Cardiovascular, Research

Left atrial appendage exclusion for prophylactic stroke reduction: LeAAPS clinical trial

[vc_row][vc_column][vc_column_text]Cardiac centers around the world are accepting patients for a clinical trial for patients undergoing cardiac surgery that may have risk factors for atrial fibrillation (A-fib) and ischemic stroke.

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Adult Services, Neuroscience, Research

Treating side effects and other lessons learned while administering Alzheimer’s drug lecanemab

A recent study published in the The Journal of Prevention of Alzheimer’s Disease provides detailed insight into clinicians’ and patients’ initial experience with lecanemab, the first Food and Drug Administration-approved antiamyloid monoclonal antibody infusion proven to slow cognitive and functional decline due to Alzheimer’s disease. Conducted at the Norton Neuroscience Institute Memory Center, the study…

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Adult Services, Diabetes, Endocrinology, Pediatric Services, Research

Meet Dr. Bala, world-renowned diabetes researcher now at Norton Healthcare and Norton Children’s

A world-renowned diabetes researcher has joined Wendy Novak Diabetes Institute, a part of Norton Healthcare and Norton Children’s, with the goal of curing Type 1 diabetes. Balamurugan N. Appakalai, Ph.D., also known as Dr. Bala, is a leading researcher in islet cell transplants and is widely considered one of the most skilled islet isolation specialists…

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Adult Services, Oncology/Hematology, Research

Phase 1 clinical trials update

Clinical research, including clinical trials, is a crucial component to advancing the discovery of cancer therapeutics. Norton Cancer Institute contributes to this advancement through participation in numerous  clinical trials every year. 4 phases of clinical trial There are four phases in a clinical trial, each with a different purpose. This helps researchers answer different questions…

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Adult Services, Endocrinology, Pediatric Services, Research

World-renowned diabetes researcher joins Wendy Novak Diabetes Institute

An internationally known researcher is joining Wendy Novak Diabetes Institute, a part of Norton Healthcare and Norton Children’s, with the goal of curing Type 1 diabetes. Norton Healthcare and Norton Children’s announced plans to build a specialized laboratory to help him and his team carry out their groundbreaking work and become a hub for diabetes research…

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Adult Services, Neuroscience, Research

Norton Research Institute unveils state-of-the-art research laboratory

Norton Research Institute will expand research efforts with the unveiling of the new Norton Research Institute Clinical & Translational Research Laboratory. The 7,200-square-foot facility, located inside Norton Healthcare Pavilion in downtown Louisville, will afford ample space and resources for scientists to conduct cutting-edge research, with the goal of producing more meaningful, applicable results directly benefiting patient…

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Adult Services, Research, Spine

Reducing risk of robot-assisted sacroiliac joint fusion complications

Robot-assisted sacroiliac joint (SIJ) fusion surgery can, in about 1% of cases, injure the superior gluteal artery (SGA), but preoperative imaging, precise robot-assisted screw insertion and soft tissue protection can mitigate risks, according to a recently published study in the Journal of Neurosurgery: Case Lessons. The study describes the case of an 80-year-old man who…

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Adult Services, Pulmonology, Research

Sotatercept FDA approval follows trial at Norton Pulmonary Specialists

Sotatercept was recently approved by the Food and Drug Administration (FDA) to treat adults with pulmonary arterial hypertension (PAH) after completing a Phase 3 clinical trial at Norton Pulmonary Specialists and other leading pulmonary hypertension centers. Sotatercept, sold under the brand name Winrevair, is a new class of therapy for pulmonary arterial hypertension. It has…

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Adult Services, Pulmonology, Research

A case study comparing a pulmonology consult with ChatGPT results

Artificial intelligence (AI) like ChatGPT can compose essays or emails, write computer code, even generate art, but how well can it manage complex patient care? A team that included Norton Healthcare researchers decided to find out. They compared ChatGPT’s recommendations for managing an 81-year-old patient with nonresolving pneumonia with those of a pulmonary specialist. “What…

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