Norton Children’s Neuroscience Institute, affiliated with UofL School of Medicine, is one of only three sites in the United States selected to participate in the TETRIS study, a clinical trial examining how remote patient monitoring can help clinicians better optimize treatment in patients diagnosed with some severe types of epilepsy. About the clinical trial The…
Minimally invasive epilepsy surgery is well tolerated and, for many children with treatment-resistant epilepsy, can lead to seizure freedom faster than families may expect — changing the course of a child’s life sooner and helping them regain a more normal childhood. “The perception of ‘epilepsy surgery’ is sometimes still associated with an earlier era of…
The patient A 43-year-old woman presented to the Norton Neuroscience Institute Face Pain Clinic with severe trigeminal neuralgia pain affecting the left side of her face. She described the pain as sharp, electrical, and shock-like — triggered by everyday activities such as eating, speaking, applying makeup and exposure to cold air. The condition progressively had…
When a child presents with a first seizure, the temptation is to order tests immediately. But the most powerful diagnostic tool is a carefully obtained history and witness description, according to Siddharth V. Jain, M.D., pediatric epileptologist with Norton Children’s Neuroscience Institute and assistant professor of pediatrics at the University of Louisville School of Medicine….
Norton Children’s is currently enrolling neonatal intensive care unit (NICU) patients in a clinical trial evaluating RLS-0071, an investigational novel peptide being studied as a treatment for hypoxic-ischemic encephalopathy (HIE) in newborns. If proven effective, it would be the first pharmacological treatment approved for the condition. The trial represents a collaboration between Norton Children’s Neonatology…
Epilepsy surgery cures roughly 60% to 80% of children with focal, drug-resistant epilepsy, yet it is still commonly positioned as a treatment of last resort. That misconception, according to Ahmad Marashly, M.D., pediatric epileptologist and director of pediatric epilepsy at Norton Children’s Neuroscience Institute, affiliated with the UofL School of Medicine, can delay referrals for…
Most pediatric neurology patients transfer to adult care between ages 18 and 23, yet there is a critical gap between transfer and transition, the long-term process of preparing patients and families for independence and self-management. For patients with neurological disorders, many of whom have intellectual or physical disabilities, this transition is particularly complex and requires…
Larry B. Goldstein, M.D., professor and chair of the Department of Neurology at UK HealthCare, delivered a compelling presentation on stroke prevention that underscores the critical role of primary care providers in reducing stroke incidence. Stroke is the fourth leading cause of death in the United States, with about 795,000 new and recurrent strokes occurring…
Nearly all individuals with dementia will experience behavioral or psychological symptoms during their disease course, presenting significant challenges for caregivers and clinicians alike. Understanding how to identify, evaluate and manage these symptoms while minimizing medication use remains essential for improving patient outcomes and quality of life. In a recent “MedChat” podcast, Rachel N. Hart, D.O., geriatric medicine…
Dementia care is experiencing a revolutionary shift. For decades, physicians had little to offer patients beyond symptomatic treatments and supportive care. Today, the medical community stands at the edge of a new era — one defined by precise biomarker testing and disease-modifying therapies that represent genuine new treatments for Alzheimer’s disease. Understanding the new treatment…
A multiple sclerosis (MS) diagnosis can change the course of a patient’s life. Symptoms can be unpredictable; independence can feel uncertain. Patients must learn to adapt to a “new normal” while holding on to hope. For Geeta A. Ganesh, M.D., MPH, neurologist at the Norton Neuroscience Institute Hussung Family Multiple Sclerosis Center, understanding that kind…
Norton Children’s Neuroscience Institute, affiliated with the UofL School of Medicine, has issued the following statement for community providers regarding the use of leucovorin in autism. There has been increasing public interest in leucovorin (also called folinic acid or known by the brand name Wellcovorin) as a possible treatment for autism. This information was devised…