Cardiovascular, Case Study, Pediatric Services

Case Study: Novel gold-plated implantable cardioverter-defibrillator in a young child with complex long QT syndrome

The patient A 4-year-old child with complex form of long QT syndrome needed surgical revision of her implantable cardioverter-defibrillator (ICD) due to device malfunction. Long QT syndrome is a congenital heart condition that predisposes affected patients to suddenly develop serious heart rhythm disturbances (for example, ventricular tachycardia/fibrillation) that can be life-threatening. In addition to taking…

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Neuroscience, Pediatric Services

Pediatric Neuropsychology in Epilepsy Care: Assessments to Guide Clinical Decision-Making

Research shows that new pediatric epilepsy patients often lack access to pediatric neuropsychology services due to the limited availability of specialized providers. Leena Mohapatra, Ph.D., pediatric neuropsychologist at Norton Children’s Neuroscience Institute, affiliated with the UofL School of Medicine, is dedicated to addressing this critical need, working primarily with children diagnosed with epilepsy or suspected…

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Case Study, Orthopedics, Pediatric Services

Case Study: Guided growth heads off Blount’s disease bowing in 12-year-old

The patient A 12-year-old male initially was seen for significant bowing of the right tibia, causing knee pain — and his mom noted increasing deformity as he was growing older. There was concern for continued bowing of the leg, causing long-term issues with the right knee. He was having mild to moderate knee pain, which…

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Endocrinology, Pediatric Services

GLP-1 receptor agonists and obesity treatment in pediatrics

The treatment landscape for childhood obesity is evolving with the introduction of glucagon-like peptide-1 (GLP-1) receptor agonists in pediatrics. These medications, which have demonstrated substantial efficacy in adults, are now showing promising results in adolescent populations. “Integrating GLP-1 receptor agonists into pediatric obesity treatment represents a significant advancement in our ability to address a growing…

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Neuroscience, Pediatric Services

Pediatric migraine: A clinical guide for practitioners

Migraine affects 37 million men, women and children in the United States and ranks among the top 10 most disabling medical conditions, according to the World Health Organization. More than 90% of patients report that migraine interferes with education, career and social activities – making early recognition and treatment in pediatric populations particularly crucial. Paul…

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Cardiovascular, Case Study, Pediatric Services

Case study: First in the region to place Impella RP Flex temporary ventricle support

The patient An 18-year-old male with a history of heart transplantation for cardiomyopathy after a durable ventricular assist device presented with progressive cardiac allograft vasculopathy (CAV) and severe diastolic graft failure. The patient presented to the cardiac intensive care unit after a recovered cardiac arrest in extremis with impending multiorgan failure. He initially underwent placement…

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Case Study, Neuroscience, Pediatric Services

Case study: Pediatric migraine patient with anxiety

Provider Team The patient The patient is a now 13-year-old girl with a history of anxiety and headaches dating back to approximately age 7, although she did not present to neurology until age 9. At that time, she was reporting approximately 15 out of 30 headache days per month and was meeting criteria for chronic…

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Neuroscience, Pediatric Services

Pediatric migraine management: Evidence-based approaches for clinicians

Pediatric migraine management requires a nuanced approach that differs significantly from adult protocols. While migraine affects up to 10% of children and adolescents, treatment decisions must account for developmental considerations, family dynamics and the substantial placebo effect observed in younger patients. This evidence-based guide synthesizes current best practices for clinicians managing pediatric migraine, from initial…

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Cardiovascular, Gastroenterology, Pediatric Services

Navigating the confluence: Gastrointestinal considerations in pediatric congenital heart disease within the medical home

Myocarditis represents a significant cause of morbidity and mortality in pediatric patients, yet its clinical presentation can be deceptively subtle. As inflammation of the heart muscle and conduction system, myocarditis affects the heart’s ability to contract effectively and maintain normal rhythm, potentially leading to sudden cardiac death even in previously healthy children. Epidemiology and risk…

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