Dementia care is experiencing a revolutionary shift. For decades, physicians had little to offer patients beyond symptomatic treatments and supportive care. Today, the medical community stands at the edge of a new era — one defined by precise biomarker testing and disease-modifying therapies that represent genuine new treatments for Alzheimer’s disease. Understanding the new treatment…
A groundbreaking clinical trial at Norton Cancer Institute is exploring whether CAR T-cell therapy —a cellular therapy originally developed to treat cancer — could provide a curative treatment for patients with severe autoimmune diseases, including systemic lupus erythematosus (SLE), myositis and scleroderma. The RESOLUTION trial, led by principal investigator Don A. Stevens, M.D., hematologist/oncologist with…
Reviewed by Anupama Raghuram, M.D., and Julio A. Ramirez, M.D. Norton Infectious Diseases Institute researchers are challenging the traditional view of pneumonia as a self- limited acute lung infection, revealing that the disease may be associated with chronic complications affecting multiple organ systems for years after initial diagnosis. Julio A. Ramirez, M.D., and Anupama Raghuram,…
The patient An active 60-year-old male with atrial fibrillation (A-fib) had been seen by Norton Heart & Vascular Institute cardiothoracic surgeon Steven M. Peterson, M.D., and after endocardial ablation was still symptomatic. His condition limited his ability to exercise and engage in his role as a soccer referee and long-distance runner. The challenge Despite five…
Hypertension management continues to evolve as new evidence reshapes diagnostic thresholds, treatment goals and therapeutic options. Now available as an on-demand continuing medical education presentation, “Hypertension 2025: What Is New – Updates in Diagnosis, Management and Renal Denervation,” given by Matthew J. Sousa, M.D., interventional cardiologist with Norton Heart & Vascular Institute, reviews key updates…
The patient A 33-year-old male with heroin use and an abscess to left arm: Workup revealed methicillin-sensitive Staphylococcus aureus bacteremia with tricuspid endocarditis and pulmonary septic emboli with cavitations and central nervous system septic emboli. This condition is common with intravenous drug use and increasing in prevalence. His course was complicated by COVID-19. The challenge…
Chest pain is one of the most common presenting complaints in primary care, yet determining which patients need specialist referral versus reassurance remains challenging. Recent guidelines have fundamentally changed the approach to these patients, and understanding the current evidence can help primary care physicians make more informed decisions about testing and referral. The initial step…
The patient A 13-year-old female presented with bilateral shin pain that began after she increased her gymnastics training from nine to 21 hours per week around nine months prior. Her right leg pain was worse than left. She was seen by an outside sports medicine specialist clinic in August of 2024 and treated with rest…
Arrhythmias represent one of the most significant challenges in adults with congenital heart disease (ACHD), constituting the leading cause of morbidity, mortality and hospitalization in this population. Understanding the appropriate use of anti-arrhythmia medications is critical for clinicians managing these complex patients. Shelby Mangeot, DNP, APRN, presented “Anti-arrhythmia Medications: A Necessary Evil” during a continuing…
The American College of Cardiology (ACC) has recognized six Norton Healthcare hospitals for demonstrated expertise and commitment in treating patients with chest pain. Norton Healthcare has the most facilities across Louisville and Southern Indiana with the ability treat a life-threatening heart attack. “This accreditation is based on national standards ensuring patients receive specific treatment in…