Tzield may delay Stage 3 Type 1 diabetes in adults and children

Recently approved Tzield (teplizumab-mzwv), is delivering breakthrough results that suggest it may delay the onset of Stage 3 Type 1 diabetes by an average of two years. The first-in-class drug is approved for adults and […]

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Ultra-fast-acting inhaled insulin, Afrezza, trialed at Norton Children’s Endocrinology

Afrezza inhaled insulin, currently approved for adults, is being tested for children in a clinical trial at Wendy Novak Diabetes Institute, a part of Norton Children’s Endocrinology, affiliated with the UofL School of Medicine. Norton […]

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DFMO medulloblastoma clinical trial examines drug’s effectiveness for high-risk cases

Researchers are recruiting pediatric medulloblastoma patients for a novel use of difluoromethylornithine (DFMO) to prevent relapse. The multisite study, sponsored by the Beat Childhood Cancer Consortium and led by Michael Angelo C. Huang, M.D., pediatric [...]

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Butyrate-producing gut bacteria a promising avenue for Alzheimer’s treatment

Butyrate-producing gut bacteria are a promising target for preventing and treating memory loss associated with Alzheimer’s disease, according to research presented recently at the Alzheimer’s Association International Conference (AAIC) in Amsterdam, Netherlands. The research in […]

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Norwood vs. COMPSII for critical left heart obstruction with prior palliation

Surgeons face two choices for infants with critical left heart obstruction who have had prior hybrid palliation: a Norwood operation or a comprehensive stage II (COMPSII). The critical left heart obstruction cohort of the multi-institutional […]

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Natural killer cell leukemia trial underway

A human Phase 1 immunotherapy clinical trial is underway using natural killer cells, or NK cells, to target relapsed or refractory acute myeloid leukemia. Acute myeloid leukemia patients who have exhausted other treatment options are [...]

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October 2023 Norton Children’s Medical Group New Providers

Rachel L. Evans, M.D. ­ Pediatric Neurology Stephanie M. Green, D.O. Pediatric Physical Medicine and Rehabilitation Kelly A. Jenkins, M.D. ­ Pediatric Orthopedic Surgery Michael S. Orangias, M.D. ­ Pediatric Pulmonology, Pediatric Sleep Medicine Huma […]

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October 2023 Norton Medical Group new providers

Jonathan P. Boland, M.D. Emergency Medicine James C. Gray IV, M.D. Emergency Medicine Stephanie Miles, M.D. Family Medicine Vladimir Pulgaron, M.D. Family Medicine Steven J. Radtke, M.D. Urogynecology Cindy Truong, D.O. Internal Medicine Michael McCool […]

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Garlove Lectureship features advancements in medicine, a look at new discoveries and technologies

The 28th Gail Klein Garlove Lectureship on Nov. 1 is titled “Advancing Precision Medicine Through New Discoveries and Technologies,” and will be presented by Sameek Roychowdhury, M.D., Ph.D., medical director of the cancer genomics laboratory […]

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When to consider genetic testing for breast cancer

At some point in their life, 1 in 8 women will develop breast cancer. Approximately 20% of breast cancer cases are familial, affecting two or more women in the same family, usually at a later […]

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Norton Children’s pioneer passes away

A local icon in the pediatric world has passed away. Richard S. “Dick” Wolf, M.D., who served as medical director of Norton Children’s Hospital from 1983 through 1995, passed away Oct. 17, 2023. In addition […]

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Thyroid weight gain myths and surprises

Patients often suspect a thyroid condition is responsible for their weight gain or their weight loss struggles. Much of the stimulus for this belief is based on the internet, according to Lisal J. Folsom, M.D., […]

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