Adult Services, Gastroenterology

Norton Healthcare first in Louisville to unveil new treatment for esophageal cancer

New technology is bringing life-changing esophageal cancer treatment to patients at Norton Audubon Hospital. William B. Evans III, M.D., gastroenterologist with Norton Gastroenterology Consultants of Louisville, is the first and only physician in Louisville to offer truFreeze spray cryotherapy for patients with esophageal cancer. “I’m proud to be the first in the city to provide…

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Adult Services, Cardiovascular

A Practical Guide to Cardiac Diagnostic Testing: Risk-Based  Strategies Every Provider Should Know

When patients present with cardiac symptoms, choosing the right cardiac diagnostic test depends on risk stratification, symptom frequency and clinical context. Here is a practical guide to navigating cardiology testing in primary care, adapted from a continuing medical education presentation by Mostafa O. El-Refai, M.D., interventional cardiologist with Norton Heart & Vascular Institute. Chest pain:…

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Adult Services, Cardiovascular, Weight Management

Reframing Cardiometabolic Care With GLP-1 Therapy as a Multisystem Treatment Strategy

Cardiometabolic care is undergoing a transformation that includes the rise of prescribing GLP-1 receptor agonists as multisystem therapeutics. “Treating diabetes, cardiovascular disease and renal or hepatic dysfunction as isolated conditions is now an outdated approach in cardiometabolic care,” said Catrina R. Hancock, PA-C, physician assistant with Norton Heart & Vascular Institute. “Instead, treatment has shifted…

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Adult Services, Cardiovascular

New atrial fibrillation guidelines emphasize early detection and personalized management

This continuing medical education presentation features Norton Heart & Vascular Institute electrophysiologist Megan E. Gruber, D.O., discussing critical updates in atrial fibrillation (A-fib) treatment based on the latest guideline revisions. Dr. Gruber provides clinicians with practical insights into the evolving approach to A-fib management, including refined classification systems that mirror heart failure staging, enhanced focus…

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Adult Services, Neuroscience

New Alzheimer’s treatment: Revolutionary advances in dementia diagnosis and care

Dementia care is experiencing a revolutionary shift. For decades, physicians had little to offer patients beyond symptomatic treatments and supportive care. Today, the medical community stands at the edge of a new era — one defined by precise biomarker testing and disease-modifying therapies that represent  genuine new treatments for Alzheimer’s disease. Understanding the new treatment…

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Adult Services, Clinical Trials, Research

CAR T-cell therapy trial offers new hope for lupus, myositis and scleroderma patients

A groundbreaking clinical trial at Norton Cancer Institute is exploring whether CAR T-cell therapy —a cellular therapy originally developed to treat cancer — could provide a curative treatment for patients with severe autoimmune diseases, including systemic lupus erythematosus (SLE), myositis and scleroderma. The RESOLUTION trial, led by principal investigator Don A. Stevens, M.D., hematologist/oncologist with…

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Adult Services, Infectious Disease, Research

New evidence suggests pneumonia drives long-term systemic disease risk

Reviewed by Anupama Raghuram, M.D., and Julio A. Ramirez, M.D. Norton Infectious Diseases Institute researchers are challenging the traditional view of pneumonia as a self- limited acute lung infection, revealing that the disease may be associated with chronic complications affecting multiple organ systems for years after initial diagnosis. Julio A. Ramirez, M.D., and Anupama Raghuram,…

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Adult Services, Cardiovascular, Case Study

Case study: Hybrid Ablation for Refractory Atrial Fibrillation Preserves Rhythm and Restores Function

The patient An active 60-year-old male with atrial fibrillation (A-fib) had been seen by Norton Heart & Vascular Institute cardiothoracic surgeon Steven M. Peterson, M.D., and after endocardial ablation was still symptomatic. His condition limited his ability to exercise and engage in his role as a soccer referee and long-distance runner. The challenge Despite five…

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Adult Services, Cardiovascular

Updates in Hypertension Management: Applying New Guidelines, Risk Stratification, and Emerging Therapies in Clinical Practice

Hypertension management continues to evolve as new evidence reshapes diagnostic thresholds, treatment goals and therapeutic options. Now available as an on-demand continuing medical education presentation, “Hypertension 2025: What Is New – Updates in Diagnosis, Management and Renal Denervation,” given by Matthew J. Sousa, M.D., interventional cardiologist with Norton Heart & Vascular Institute, reviews key updates…

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Adult Services, Cardiovascular, Case Study

Advanced management of tricuspid endocarditis: A case study in a multidisciplinary care

The patient A 33-year-old male with heroin use and an abscess to left arm: Workup revealed methicillin-sensitive Staphylococcus aureus bacteremia with tricuspid endocarditis and pulmonary septic emboli with cavitations and central nervous system septic emboli. This condition is common with intravenous drug use and increasing in prevalence. His course was complicated by COVID-19. The challenge…

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