Research Archives - Norton Healthcare Provider

World-renowned diabetes researcher joins Wendy Novak Diabetes Institute

An internationally known researcher is joining Wendy Novak Diabetes Institute, a part of Norton Healthcare and Norton Children’s, with the goal of curing Type 1 diabetes. Norton Healthcare and Norton Children’s announced plans to build a […]

Phase 1 cystic fibrosis trial studying novel enzyme replacement therapy in adults

Patients 18 years of age and older with cystic fibrosis now have an option of participating in a Phase 1 trial of a novel, broad-spectrum, orally delivered enzyme replacement therapy for cystic fibrosis (CF). The [...]

Open-access, peer-reviewed medical journal accepting submissions

Norton Healthcare has launched a new, open-access medical journal to promote the sharing of innovation and ideas from the laboratory, the bedside and everyday practice. Norton Healthcare Medical Journal welcomes original articles related to medicine, […]

Louisville Business First has recognized Norton Healthcare and Norton Children’s research team members with its 2024 Health Care Heroes Innovator Award

Louisville Business First has recognized researchers at Norton Healthcare with its 2024 Health Care Heroes Innovator Award. The award honors those who break ground in the health care field by developing or implementing new technology, [...]

Implementing principles of trauma-informed care

Reviewed by Amber L. Pendleton, M.D. Implementing the principles of trauma-informed care across a primary care team and community resources provides an opportunity to focus on adverse childhood experiences and social-care needs, with the potential […]

Essentials of clinical trials

Clinical trials and studies, which are essential to the development of new drugs and treatments, need to be conducted under strict ethical, clinical and investigational structures. The most common are investigational trials with new medications [...]

Study of Paxlovid for children with COVID-19 underway at Norton Children’s Research Institute

Norton Children’s Research Institute, affiliated with the UofL School of Medicine, is involved in a study to evaluate the safety, pharmacokinetics and efficacy of nirmatrelvir/ritonavir (authorized as Paxlovid in older children and adults) in symptomatic [...]

Clinical research: Asking questions, sharing answers

Clinical research drives progress for every element of health and requires global collaboration. At Norton Healthcare alone, our research teams lead and contribute to studies about pediatric medicine, cancer, infectious diseases, cardiology, neurology, the spine, […]

Study shows low-dose cadmium threshold for testicular ferroptosis in mice

Cadmium, a natural element used for rechargeable batteries and other industrial applications, can induce a novel type of testicular cell death in mice after low-dose exposure, according to a groundbreaking study. Cadmium is known to […]

Anti-CD20 monoclonal antibody therapy for relapsing MS in adult patients

Anti-CD20 monoclonal antibody therapy represents a major advance in treating relapsing multiple sclerosis (MS) in adult patients, reducing relapse risk and mitigating disability progression. These monoclonal antibody therapies deplete circulating B cells by targeting CD20, [...]

Reduced-toxicity myeloablative conditioning regimen effective against high-risk pediatric leukemias

A low-toxicity myeloablative conditioning regimen is safe and effective in treating high-risk leukemias, particularly myeloid disease, according to a study recently published in the journal Pediatric Blood & Cancer. Conventional myeloablative conditioning is effective at […]

Offering the latest childhood brain tumor therapies so kids and their families don’t have to travel far from home

Brain tumors are now the leading cause of cancer-related deaths among children. Year after year, Kentucky ranks among states with the highest incidence of children with brain tumors, and Kentucky currently ranks third in the [...]

Category: Research